Effect of Alpha Lipoic Acid and Pyridine Group on Silicone Hydrogel Lens
* 본 문서는 배포용으로 복사 및 편집이 불가합니다.
서지정보
ㆍ발행기관 : 대한시과학회
ㆍ수록지정보 : 대한시과학회지 / 25권 / 4호
ㆍ저자명 : Seon-Young Park, A-Young Sung
ㆍ저자명 : Seon-Young Park, A-Young Sung
목차
Ⅰ. IntroductionⅡ. Materials and Methods
1. Reagents and Materials
2. Polymerization
3. Analysis
Ⅲ. Results
1. Properties of Alpha Lipoic Acid
2. Properties of Pyridine
3. Properties of Alpha Lipoic Acid PyridineCombination
Ⅳ. Discussion
Ⅴ. Conclusion
References
영어 초록
Abstract Purpose : In this study, α-Lipoic acid and pyridine were added to hydrogel materials and silicone hydrogel materials, respectively, to manufacture contact lens to evaluate changes in physical properties. Methods : N,N-Dimethylacrylamide (DMA), 2,2'-Azobis (2-methylpropionitrile) (AIBN), an initiator, and Ethylene glycol dimethacrylate (EGDMA), crosslinking agent, were used basic mixing ratio, and hydrogel materials were prepared by thermopolymerization at 100°C for 1 hour based on 2-Hydroxyethyl methacrylate (HEMA). Silicone hydrogel materials were prepared by thermopolymerization at 130°C for 2 hours based on Silicone monomer (SID). The properties of contact lenses were evaluated by adding 0.05% of 3-hydroxypyridine N-oxide and (R)-(+)-α-Lipoic acid by ratio to each material. Results : A lens manufactured by adding alpha lipoic acid to silicone hydrogel materials showed a tendency to increase wettability and decrease refractive index. A lens manufactured by adding pyridine to silicone hydrogel materials showed UV-A blocking ability, and the refractive index tended to increase. In addition, a contact lens manufactured by adding alpha lipoic acid and pyridine together showed antimicrobial properties, reduced surface roughness, and increased wettability and oxygen permeability according to the ratio of alpha lipoic acid addition. Conclusion : It is judged that alpha lipoic acid and pyridine are expected to improve wettability and oxygen permeability of the lens and to be used as contact lens materials with antibacterial properties. Key words : Alpha lipoic acid, Antimicrobial, Oxygen permeability, Pyridine, Wettability참고 자료
없음"대한시과학회지"의 다른 논문
- Prevalence and Risk Factors of Dry Eye Syndrome in Univ..10페이지
- A Study on the Corneal Curvature in Refractive Surgery ..8페이지
- Effect of Amount of Astigmatism on Vertical Heterophori..10페이지
- A Study on the Correlation between Ocular Dimensions ac..20페이지
- Differences and Reliability Evaluation of Interpupillar..6페이지
- The Knowledge and Healthy Life Practices for Glaucoma P..13페이지
- A Study on Awareness and Performance Satisfaction of th..12페이지
- Utilization Functional Analysis and Crosslinking Agents..10페이지
- A Study on Development for the Korean Optometrists Syst..11페이지
- Self-Assessment of Soft Contact Lens Wear and Care amon..13페이지