[A+] Report Synthesis of 3-hexylthiophene (3-hexylthiophene 합성 레포트)

소개글

"Report Synthesis of 3-hexylthiophene (3-hexylthiophene 합성 레포트)"에 대한 내용입니다.

목차

1. Introduction
1) Purpose of the Experiment
2) Theoretical Background

2. Method
1)Materials
2) Procedure

3. Result & Discussion

4. Conclusion

본문내용

- Purpose
To synthesize 3-hexylthiophene using Grignard Reaction

- Theoretical Background
1. Grignard reaction
Grignard reaction is an organometallic chemical reaction in which alkyl, allyl, vinyl, and aryl-magnesium halides are added to the carbonyl group in aldehyde or ketone.

2. Kumada coupling
Kumada coupling is a type of cross coupling reaction that is useful for producing carbon-carbon bonds by the reaction of Grignard reagents and organic halides.

참고 자료

Wade, L. G., & Simek, J. W. (2017). Organic chemistry (9th ed.). Glenview, IL: Pearson.
Smith, M. B. (2019), Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (8th ed.), New York: Wiley
Corriu, R. J. P. & Masse, J. P. (1972, January 1). "Activation of Grignard reagents by transition-metal complexes. A new and simple synthesis of trans-stilbenes and polyphenyls". Journal of the Chemical Society, Chemical Communications (3): 144a. doi:10.1039/C3972000144A
1,3-Bis(diphenylphosphino)propane Nickel(II) Chloride. American Elements, (2017, June 13). Retrieved March 18, 2021, from https://www.americanelements.com/1-3-bis-diphenylphosphino-propane-nickel-ii-chloride-15629-92-2
Tetrahydrofuran. Sigma-Aldrich, (n.d.). Retrieved March 18, 2021, from https://www.sigmaaldrich.com/chemistry/solvents/tetrahydrofuran-center.html