[생체의용고분자] REVIEW 논문 PPT 간단 정리 (영문)

소개

"[생체의용고분자] REVIEW 논문 PPT 간단 정리 (영문)"에 대한 내용입니다.

도움이 되었으면 좋겠습니다. 감사합니다.

(논문 : An Overview of Poly(lactic-co-glycolic) Acid (PLGA)-Based Biomaterials for Bone Tissue Engineering, Enjoy your Piergiorgio Gentile, Valeria Chiono, Irene Carmagnola and Paul V. Hatton, Int. J. Mol. Sci. 2014, 15, P.3640-P.3659)

목차

1. Introduction

2. Chemistry
2.1. Synthesis
2.2. Physico-Chemical Properties

3. Applications in Bone Tissue Engineering
3.1. Porous PLGA-HA Scaffolds
3.2. Fibrous Scaffolds
3.3. Hydrogels
3.4. Injectable Microspheres

4. Current Trends in the Development of Functionalized PLGA Constructs

5. Conclusions and Future Prospects

본문내용

▪ Bone tissue engineering
- A research field with many clinical applications
- Bone replacement in the case of orthopaedic defects, bone neoplasia and tumours, pseudoarthrosis treatment, stabilization of spinal segments, maxillofacial, craniofacial, orthopaedic, etc

▪ Scaffolds
- The strategy of designing synthetic bone substitutes
➡ For healing diseased or damaged bone tissue
➡ Promising alternative ; allografts, autografts, and xenografts
- Should be based on biomaterials with adequate properties

참고자료

· PART’s slide background image ; Scaffold image (https://www.bonusbiogroup.com/index.php/science-and-technology/bone-tissue-engineering)
· Chan Woo Lee, Development of Medical Resorbable Composite Materials Interposed in the Poly(glycol acid), Polymer(Korea), Vol.31, No.3, pp.228-232 (2007)
· Li, J.,Stayshich, R.M. and Meyer, T.Y., Exploiting sequence to control the hydrolysis behavior of biodegradable PLGA copolymers, J. Am. Chem. Soc., 133, pp.6910-6913 (2011)
· S.S. Kim, K.m.Ahn, M.S.Park, J.H.Lee, C.Y.Choi and B.S. Kim, A poly(lactide-co-glycolide)/hydroxyapatite composite scaffold with enhanced osteoconductivity, Journal of Biomedical Materials Research, Part A DOI, Inc. pp.206-215 (2006)
· Y.J.Seol, T.Y.Kang and D.W.Cho, Solid freeform fabrication technology applied to tissue engineering with various biomaterials, The Royal Society of Chemistry, Soft Matter, 8, pp.1730–1735 (2012)
· Huang, Z.M., Zhang, Y.Z., Kotaki, M. and Ramakrishna, S. A , Review on polymer nanofibers by electrospinning and their applications in nanocomposites. Compos. Sci. Technol. , 63, pp.2223–2253 (2003)
· Y.S.Jung, W.R.Park, HJ.Park, D.K.Lee and K.Na, Thermo-sensitive injectable hydrogel based on the physical mixing of hyaluronic acid and Pluronic F-127 for sustained NSAID delivery, Carbohydrate Polymers 156, pp.403–408 (2017)
· GRGDSPC, Chemical book, https://www.chemicalbook.com/ChemicalProductProperty_KR_CB1703980.htm