The purpose of this study was to examine the effects of a 12 weeks combined exercise training program on inflammatory markers and adiponectin concentrations in overweight and obese university women. Twenty-seven younger (19.7±1.9 year) subjects participated in this study. They completed 12 weeks (3 days/week) of aerobic and resistance exercises. Blood samples were collected before and after the 12 week period, and the concentrations of serum C-reactive protein (CRP), plasma interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and adiponectin were determined using separate ELISA. Body weight (p<.001), fat mass (p<.001), percent fat (p<.001) and waist circumference (p=.001) were all significantly decreased after the 12 week exercise program. TNF-α was significantly decreased (p<.001), but IL-6 was significantly increased (p=.010) after 12 week exercise program. However, CRP and adiponecin were not changed after 12 week exercise program. These results support that the use of combined aerobic and resistance training as a modality to reduce the risk of cardiovascular disease development as defined by a decrease in serum TNF-α concentration in healthy young overweight and obese women.
영어초록
The purpose of this study was to examine the effects of a 12 weeks combined exercise training program on inflammatory markers and adiponectin concentrations in overweight and obese university women. Twenty-seven younger (19.7±1.9 year) subjects participated in this study. They completed 12 weeks (3 days/week) of aerobic and resistance exercises. Blood samples were collected before and after the 12 week period, and the concentrations of serum C-reactive protein (CRP), plasma interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and adiponectin were determined using separate ELISA. Body weight (p<.001), fat mass (p<.001), percent fat (p<.001) and waist circumference (p=.001) were all significantly decreased after the 12 week exercise program. TNF-α was significantly decreased (p<.001), but IL-6 was significantly increased (p=.010) after 12 week exercise program. However, CRP and adiponecin were not changed after 12 week exercise program. These results support that the use of combined aerobic and resistance training as a modality to reduce the risk of cardiovascular disease development as defined by a decrease in serum TNF-α concentration in healthy young overweight and obese women.
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