위장의 위장관 기질종양 환자에서 개복 쐐기절제술과 복강경적 쐐기절제술의 비교 (Comparison of Clinical Characteristics between Open and Laparoscopic Surgery Groups in Gastric Gastrointestinal Stromal Tumor Patients)

서지정보

· 발행기관 : 대한외과학회
· 수록지 정보 : Annals of Surgical Treatment and Research / 79권 / 6호 / 455 ~ 459페이지
· 저자명 : 배정민, 김세원, 김상운, 송선교

초록

Purpose: The stomach is the most frequent site of gastrointestinal stromal tumor (GIST). Surgery remains the only curative treatment for GIST. Resection needs to ensure tumor free margin without lymphadenectomy. Thus partial gastric resection is the treatment of choice for gastric GIST. This study aims to review clinical characteristics between open and laparoscopic wedge resection group and evaluate safety and efficacy of laparoscopic wedge resection.
Methods: Between 1997 and 2008, 74 consecutive patients undergoing open or laparoscopic wedge resection of gastric GISTs were identified in a retrospectively collected database. Preoperative and postoperative variables were analyzed.
Results: Wedge resection with negative margin was performed in 74 patients. Laparoscopic wedge resection was performed 19 patients. Open wedge resection was performed in 55 patients. Mean tumor size of laparoscopic group was 2.7 cm (range 0.4∼6.0) and open group was 4.4 cm (range 0.4∼23.0). Mean operation time of laparoscopic group was 150.0 minutes (range 80∼240), and open group was 164.6 minutes (range 75∼360). Mean hospital stay of laparoscopic group was 7.11 days (range 3∼19), and open group was 9.38 days (range 6∼20). There were no significant survival differences between groups.
Conclusion: A laparoscopic wedge resection of gastric GIST is associated with short hospitalization and not inferior to open wedge resection in terms of morbidity and mortality. The long-term outcomes between laparoscopic and open wedge resection group in our study were no significant survival differences. Long-term and prospective randomized study should be performed to confirm oncological safety of laparoscopic wedge resection.

영어초록

Purpose: The stomach is the most frequent site of gastrointestinal stromal tumor (GIST). Surgery remains the only curative treatment for GIST. Resection needs to ensure tumor free margin without lymphadenectomy. Thus partial gastric resection is the treatment of choice for gastric GIST. This study aims to review clinical characteristics between open and laparoscopic wedge resection group and evaluate safety and efficacy of laparoscopic wedge resection.
Methods: Between 1997 and 2008, 74 consecutive patients undergoing open or laparoscopic wedge resection of gastric GISTs were identified in a retrospectively collected database. Preoperative and postoperative variables were analyzed.
Results: Wedge resection with negative margin was performed in 74 patients. Laparoscopic wedge resection was performed 19 patients. Open wedge resection was performed in 55 patients. Mean tumor size of laparoscopic group was 2.7 cm (range 0.4∼6.0) and open group was 4.4 cm (range 0.4∼23.0). Mean operation time of laparoscopic group was 150.0 minutes (range 80∼240), and open group was 164.6 minutes (range 75∼360). Mean hospital stay of laparoscopic group was 7.11 days (range 3∼19), and open group was 9.38 days (range 6∼20). There were no significant survival differences between groups.
Conclusion: A laparoscopic wedge resection of gastric GIST is associated with short hospitalization and not inferior to open wedge resection in terms of morbidity and mortality. The long-term outcomes between laparoscopic and open wedge resection group in our study were no significant survival differences. Long-term and prospective randomized study should be performed to confirm oncological safety of laparoscopic wedge resection.

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