Microscopic Study of Decomposition-Inhibition in Stabilized ClO2 Gas in Skeletal Muscle of Rat

서지정보

· 발행기관 : 한국현미경학회
· 수록지 정보 : Applied Microscopy / 41권 / 4호 / 277 ~ 284페이지
· 저자명 : 황규성, 정문진, 정순정, 안용순, 임도선

초록

This study was conducted to determine the antiseptic effect of stabilized chlorine dioxide (S-ClO2) on muscle tissue of rats. Skeletal muscle of 8-week old Sprague-Dawley rats was used. Light and transmission electron microscopic findings were observed in the control group, which was not treated with stabilized chlorine dioxide, and in the experimental group, which was treated with a stabilized chlorine dioxide powder in aqueous solution.
According to the LM and TEM observations, the day 1 control group showed the initiation of endomysium collapse resulting in an unclear boundary of muscle fibers, and partial collapse of the mitochondrial membranes. All endomysium had collapsed, and bacteria were observed among muscle fibers in the day 2 and later groups. Shapes of muscles were not distinguishable in day 3 or later groups. In contrast, the day 1 and 3 experimental groups revealed detailed structure of typical muscles, but partial collapse of the mitochondrial membranes was observed in the day 3 and later groups.
Subsequently, connective tissues collapsed and structures in the shape of concentric circles were observed.
In summary, the day 1 control group showed the initial collapse of tissues, and shapes were not distinguishable in the day 3 and later groups because most of the tissues had collapsed. In contrast, the day 3 experimental group showed partial collapse, but the overall shapes of muscles were maintained as time went on, confirming the antiseptic effect of stabilized chlorine dioxide on muscles.

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