일측성 만성 이명 환자에서 1회 경두개 자기장 치료의 단기 효과 (Short-Term Effect of Single Session Repetitive Transcranial Magnetic Stimulation in Chronic Unilateral Tinnitus)

서지정보

· 발행기관 : 대한이비인후과학회
· 수록지 정보 : 대한이비인후-두경부외과학회지 / 55권 / 4호 / 216 ~ 221페이지
· 저자명 : 강호민, 박문서, 이호윤, 이선규, 변재용, 여승근

초록

Background and Objectives The repetitive Transcranial Magnetic Stimulation (rTMS) is generally performed over the course of several weeks, as its theoretical and experimental validity has been identified in repetitive procedures. If short term application of rTMS is proven to be significantly effective, more effective treatment of tinnitus can be expected. This study was conducted to measure the effect of one session of sham rTMS & one real trial of rTMS in chronic unilateral tinnitus patients.
Subjects and Method rTMS stimulation of 1 Hz and 100% magnitude was given 1200 times per day to 33 patients with chronic unilateral tinnitus on their left side, between T3 and C3/T5, following the convention of the 10-20 International EEG system. Visual Analogue Scale (VAS) and Tinnitus Handicap Inventory (THI) scores were measured four times-immediately before rTMS, immediately after sham rTMS, immediately after real rTMS and two weeks after real rTMS.
Results VAS and THI scores were found to show a tendency of declining. Immediately after real rTMS application, a significant decrease in VAS and THI scores was observed compared to those measured immediately before rTMS (p＜0.05). The longer the duration was, the smaller the changes in THI and VAS scores were after a single session of rTMS treatment, a finding that is statistically significant (p＜0.05). No significant changes in THI and VAS scores (p＞0.05) attributable to the direction of tinnitus were observed.
Conclusion A single session rTMS is thought to be a possible adjunctive treatment for tem-porary relief of tinnitus.

영어초록

Background and Objectives The repetitive Transcranial Magnetic Stimulation (rTMS) is generally performed over the course of several weeks, as its theoretical and experimental validity has been identified in repetitive procedures. If short term application of rTMS is proven to be significantly effective, more effective treatment of tinnitus can be expected. This study was conducted to measure the effect of one session of sham rTMS & one real trial of rTMS in chronic unilateral tinnitus patients.
Subjects and Method rTMS stimulation of 1 Hz and 100% magnitude was given 1200 times per day to 33 patients with chronic unilateral tinnitus on their left side, between T3 and C3/T5, following the convention of the 10-20 International EEG system. Visual Analogue Scale (VAS) and Tinnitus Handicap Inventory (THI) scores were measured four times-immediately before rTMS, immediately after sham rTMS, immediately after real rTMS and two weeks after real rTMS.
Results VAS and THI scores were found to show a tendency of declining. Immediately after real rTMS application, a significant decrease in VAS and THI scores was observed compared to those measured immediately before rTMS (p＜0.05). The longer the duration was, the smaller the changes in THI and VAS scores were after a single session of rTMS treatment, a finding that is statistically significant (p＜0.05). No significant changes in THI and VAS scores (p＞0.05) attributable to the direction of tinnitus were observed.
Conclusion A single session rTMS is thought to be a possible adjunctive treatment for tem-porary relief of tinnitus.

참고자료

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